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Table 2 Univariate and multivariate linear regression analyses for the parameters predicting CHA2DS2-VASc score

From: Clinical and genetic relationships between the QTc interval and risk of a stroke among atrial fibrillation patients undergoing catheter ablation

 

Univariate

Multivariate

 

β

95% CI

p value

β

95% CI

p value

Age

0.081

0.076–0.086

< 0.001

− 6.43E−5

− 2.21E−4–9.28E−5

0.422

CHF

1.442

1.133–1.752

< 0.001

0.998

0.993–1.003

< 0.001

HTN

1.698

1.579–1.816

< 0.001

1.001

0.998–1.003

< 0.001

DM

1.942

1.757–2.126

< 0.001

0.998

0.995–1.002

< 0.001

Age ≥ 75 years

1.519

1.382–1.657

< 0.001

1.000

0.997–1.003

< 0.001

Age 65–74 years

1.546

1.398–1.695

< 0.001

1.003

0.999–1.006

< 0.001

Prior stroke/TIA

1.354

1.262–1.447

< 0.001

0.999

0.998–1.001

< 0.001

Vascular disease

1.988

1.764–2.211

< 0.001

1.006

1.002–1.010

< 0.001

Female sex

1.289

1.144–1.433

< 0.001

0.999

0.996–1.001

< 0.001

PAF

− 0.253

− 0.424 to − 0.083

0.004

− 0.002

− 0.005–0.001

0.136

BMI

1.94E−4

− 0.001–0.002

0.803

   

LA dimension

0.049

0.043–0.055

< 0.001

3.22E−5

− 1.79E−4–2.44E−4

0.765

PR interval

0.004

0.001–0.006

0.002

− 1.13E−5

− 5.08E−5–2.83E−5

0.576

QRS

− 0.009

− 0.013 to − 0.004

< 0.001

− 8.84E−6

−8.91E−5–7.14E−5

0.829

QTc interval

0.014

0.012–0.015

< 0.001

4.63E−5

3.57E−6–8.90E−5

0.034

  1. β, regression coefficient; BMI, body mass index; CHF, congestive heart failure; CI, confidence interval; DM, diabetes mellitus; HTN, hypertension; LA, left atrial; PAF, paroxysmal atrial fibrillation; TIA, transient ischemic attack