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Table 1 Baseline characteristics of patients

From: Differences in anticoagulation strategy and outcome in atrial fibrillation patients with chronic kidney disease: a CODE-AF registry study

 Normal (n = 2176)CKD (n = 1129)p value
Female, n709 (32.6)535 (47.4)0.001
Age, years63.7 (58.0–71.0)75.0 (71.0–80.0)0.001
Weight, kg69.8 ± 11.059.7 ± 10.00.001
BMI, kg/m225.4 ± 3.223.2 ± 3.20.001
eGFR, mL min−1 1.73 m−285.5 (69.5–95.1)44.5 (39.0–54.0)0.001
Paroxysmal AF1463 (67.2)722 (64.0)0.067
Persistent AF612 (28.1)346 (30.6)0.067
Permanent AF101 (4.6)61 (5.4)0.067
CHA2DS2-VASc score2.3 (1.0–3.0)3.7 (3.0–5.0)0.001
HAS-BLED score1.7 (1.0–2.0)2.4 (2.0–3.0)0.001
Heart failure186 (8.5)188 (16.7)0.001
Hypertension1407 (64.7)863 (76.4)0.001
Diabetes mellitus516 (23.7)378 (33.5)0.001
Stroke/TIA309 (14.3)250 (22.2)0.001
Myocardial infarction76 (3.5)55 (4.9)0.054
PAD98 (4.5)77 (6.8)0.009
History of bleeding217 (10.0)155 (13.7)0.43
ICD insertion27 (1.2)16 (1.4)0.671
Pacemaker insertion98 (4.5)128 (11.3)0.001
Dyslipidemia743 (34.1)404 (35.8)0.348
Cancer203 (9.3)130 (11.5)0.048
LA volume, mL/m253.9 ± 29.068.4 ± 40.40.001
LVEF, %60.2 ± 20.258.6 ± 9.60.149
Follow-up duration, months10.5 (9.5–12.3)10.7 (9.5–12.3)0.051
  1. Data are presented as mean ± standard deviation or number (percentage)
  2. AF, atrial fibrillation; BMI, body mass index; CHA2DS2-VASc, Congestive heart failure, Hypertension, Age 75 years or older, Diabetes mellitus, previous Stroke/transient ischemic attack, Vascular disease, Age 65 to 74 years, Sex category (female); CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; HAS-BLED, Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly, Drugs/alcohol concomitantly; ICD, implantable cardioverter defibrillator; LA, left atrial; LVEF, left ventricular ejection fraction; PAD, peripheral artery disease; TIA, transient ischemic attack