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Table 1 Baseline characteristics of patients

From: Differences in anticoagulation strategy and outcome in atrial fibrillation patients with chronic kidney disease: a CODE-AF registry study

 

Normal (n = 2176)

CKD (n = 1129)

p value

Female, n

709 (32.6)

535 (47.4)

0.001

Age, years

63.7 (58.0–71.0)

75.0 (71.0–80.0)

0.001

Weight, kg

69.8 ± 11.0

59.7 ± 10.0

0.001

BMI, kg/m2

25.4 ± 3.2

23.2 ± 3.2

0.001

eGFR, mL min−1 1.73 m−2

85.5 (69.5–95.1)

44.5 (39.0–54.0)

0.001

Paroxysmal AF

1463 (67.2)

722 (64.0)

0.067

Persistent AF

612 (28.1)

346 (30.6)

0.067

Permanent AF

101 (4.6)

61 (5.4)

0.067

CHA2DS2-VASc score

2.3 (1.0–3.0)

3.7 (3.0–5.0)

0.001

HAS-BLED score

1.7 (1.0–2.0)

2.4 (2.0–3.0)

0.001

Heart failure

186 (8.5)

188 (16.7)

0.001

Hypertension

1407 (64.7)

863 (76.4)

0.001

Diabetes mellitus

516 (23.7)

378 (33.5)

0.001

Stroke/TIA

309 (14.3)

250 (22.2)

0.001

Myocardial infarction

76 (3.5)

55 (4.9)

0.054

PAD

98 (4.5)

77 (6.8)

0.009

History of bleeding

217 (10.0)

155 (13.7)

0.43

ICD insertion

27 (1.2)

16 (1.4)

0.671

Pacemaker insertion

98 (4.5)

128 (11.3)

0.001

Dyslipidemia

743 (34.1)

404 (35.8)

0.348

Cancer

203 (9.3)

130 (11.5)

0.048

LA volume, mL/m2

53.9 ± 29.0

68.4 ± 40.4

0.001

LVEF, %

60.2 ± 20.2

58.6 ± 9.6

0.149

Follow-up duration, months

10.5 (9.5–12.3)

10.7 (9.5–12.3)

0.051

  1. Data are presented as mean ± standard deviation or number (percentage)
  2. AF, atrial fibrillation; BMI, body mass index; CHA2DS2-VASc, Congestive heart failure, Hypertension, Age 75 years or older, Diabetes mellitus, previous Stroke/transient ischemic attack, Vascular disease, Age 65 to 74 years, Sex category (female); CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; HAS-BLED, Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly, Drugs/alcohol concomitantly; ICD, implantable cardioverter defibrillator; LA, left atrial; LVEF, left ventricular ejection fraction; PAD, peripheral artery disease; TIA, transient ischemic attack