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Table 2 Univariate and multivariate logistic regression analysis for predictors of poor anticoagulant control on warfarin (TTR < 65%) in NVAF patients

From: Factors predicting poor anticoagulant control on warfarin in a Thai population with non-valvular atrial fibrillation (NVAF): the ACAChE score

 

Univariable analysis

Multivariable analysis

Crude odd ratio (95%CI)

p value

Adjusted odd ratio (95%CI)

p value

Age ≥ 75 years

1.53 (1.12–2.07)

0.007‡

1.4 (1.02–1.93)

0.037

Female

0.96 (0.71–1.31)

0.809

  

BMI ≥ 25 kg/m2

0.68 (0.50–0.92)

0.012‡

  

Education

Primary or no

1.48 (1.02–2.16)

0.041‡

  

Secondary

1.24 (0.82–1.88)

0.312

  

Smoking

Current smoker

0.97 (0.49–1.93)

0.935

  

Ex-smoker

0.87 (0.62–1.23)

0.434

  

Diabetes mellitus

1.44 (1.05–1.98)

0.025‡

  

Heart failure

2.14 (1.29–3.53)

0.003‡

1.7 (1.01–2.86)

0.047

Hepatic impairment

1.64 (1.06–2.52)

0.025‡

  

CKD (GFR < 50 ml/min/1.73 m2)

2.10 (1.42–3.11)

< 0.001‡

1.68 (1.12–2.52)

0.013

LVEF < 40%

2.33 (1.30–4.19)

0.005‡

1.92 (1.04–3.53)

0.037

Antiplatelet use

4.10 (2.16–7.77)

< 0.001‡

3.49 (1.82–6.66)

 < 0.001

  1. p value < 0.05