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Table 2 Univariate and multivariate logistic regression analysis for predictors of poor anticoagulant control on warfarin (TTR < 65%) in NVAF patients

From: Factors predicting poor anticoagulant control on warfarin in a Thai population with non-valvular atrial fibrillation (NVAF): the ACAChE score

  Univariable analysis Multivariable analysis
Crude odd ratio (95%CI) p value Adjusted odd ratio (95%CI) p value
Age ≥ 75 years 1.53 (1.12–2.07) 0.007‡ 1.4 (1.02–1.93) 0.037
Female 0.96 (0.71–1.31) 0.809   
BMI ≥ 25 kg/m2 0.68 (0.50–0.92) 0.012‡   
Education
Primary or no 1.48 (1.02–2.16) 0.041‡   
Secondary 1.24 (0.82–1.88) 0.312   
Smoking
Current smoker 0.97 (0.49–1.93) 0.935   
Ex-smoker 0.87 (0.62–1.23) 0.434   
Diabetes mellitus 1.44 (1.05–1.98) 0.025‡   
Heart failure 2.14 (1.29–3.53) 0.003‡ 1.7 (1.01–2.86) 0.047
Hepatic impairment 1.64 (1.06–2.52) 0.025‡   
CKD (GFR < 50 ml/min/1.73 m2) 2.10 (1.42–3.11) < 0.001‡ 1.68 (1.12–2.52) 0.013
LVEF < 40% 2.33 (1.30–4.19) 0.005‡ 1.92 (1.04–3.53) 0.037
Antiplatelet use 4.10 (2.16–7.77) < 0.001‡ 3.49 (1.82–6.66)  < 0.001
  1. p value < 0.05