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Table 4 Different cutoff points of the ACAChE score to predict poor anticoagulant control on warfarin (TTR < 65%)

From: Factors predicting poor anticoagulant control on warfarin in a Thai population with non-valvular atrial fibrillation (NVAF): the ACAChE score

  ACAChE score ≥ 1
TTR < 65%
ACAChE score ≥ 2
TTR < 65%
ACAChE score ≥ 3
TTR < 65%
ACAChE score ≥ 4
TTR < 65%
ACAChE score ≥ 5
TTR < 65%
ACAChE score ≥ 6
TTR < 65%
ACAChE score ≥ 7
TTR < 65%
Sensitivity 97.3
(95.8–98.4)
95.8
(93.9–97.2)
68.1
(64.4–71.7)
43.8
(39.9–47.8)
35
(31.3–38.9)
19.5
(16.5–22.8)
13.8
(11.2–16.7)
Specificity 2.65
(0.98–5.69)
3.54
(1.54–6.86)
47.3
(40.7–54.1)
75.2
(69.1–80.7)
83.2
(77.7–87.8)
93.4
(89.3–96.2)
95.1
(91.5–97.5)
Likelihood ratio (+) 1.00
(0.975–1.03)
0.993
(0.964–1.02)
1.29
(1.13–1.48)
1.77
(1.39–2.26)
2.08
(1.53–2.83)
2.93
(1.75–4.9)
2.84
(1.55–5.21)
Likelihood ratio (−) 1.01
(0.401–2.52)
1.2
(0.552–2.6)
0.673
(0.563–0.804)
0.747
(0.675–0.827)
0.781
(0.72–0.848)
0.863
(0.819–0.908)
0.906
(0.868–0.946)
Odd ratio 0.995
(0.399–2.48)
0.829
(0.378–1.82)
1.92
(1.41–2.62)
2.37
(1.69–3.32)
2.66
(1.82–3.91)
3.4
(1.96–5.91)
3.13
(1.66–5.92)
Positive predictive value 73.8
(70.7–76.8)
73.7
(70.5–76.6)
78.5
(74.8–81.8)
83.3
(78.8–87.1)
85.4
(80.6–89.5)
89.2
(82.8–93.8)
88.9
(81–94.3)
Negative predictive value 26.1
(10.2–48.4)
22.9
(10.4–40.1)
34.5
(29.2–40.1)
32.2
(28.2–36.4)
31.2
(27.5–35.1)
29.1
(25.9–32.6)
28.1
(25–31.5)
Accuracy 72.54
(69.43–75.49)
71.61
(68.47–74.6)
62.69
(59.36–65.93)
52.03
(48.63–55.41)
47.62
(47.71–54.49)
38.82
(35.55–42.16)
35.11
(31.92–38.4)
p value 0.991 0.647 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001