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Table 1 Association between atrial fibrillation and dementia

From: Lower dementia risk with anticoagulation and ablation in patients with atrial fibrillation

Study (Year of publication) Follow-up duration (years) Age (years) of population (mean or median) Types of dementia Incidence of dementia Increased dementia risk for AF (OR or HR [95% CI])
AF   No AF
Ott et al. [10]
(1997)
Cross-sectional 67.9 All-cause -   - 2.3 (1.4–3.7)
AD -   - 1.8 (1.0–3.3)
VaD -   - 1.9 (0.6–5.5)
Bunch et al. [7] (2010) 5.3 60.6 All-cause 3.3%   1.3% 1.44
AD 1.5%   0.7% 1.06
SD 1.6%   0.6% 1.39
VaD 0.9%   0.3% 1.73
Dublin et al. [11] (2011) 6.8 74.3 All-cause 4.8%/yr   2.5%/yr 1.38 (1.10–1.73)
AD 3.8%/yr   2.0%/yr 1.50 (1.16–1.94)
Marengoni et al. [12] (2011) 4.0 78 All-cause 7.2%/yr   6.4%/yr 0.9 (0.5–1.7)
AD 5.5%/yr   5.2%/yr 0.8 (0.4–1.5)
Kim et al. [8] (2019) 7.2 71.7 All-cause 4.1%/yr   2.7%/yr 1.52 (1.43–1.63)
AD 2.2%/yr   1.6%/yr 1.31 (1.20–1.43)
VaD 1.1%/yr   0.5%/yr 2.11 (1.85–2.41)
  1. AD Alzheimer’s disease, AF atrial fibrillation, CI confidence interval, HR hazard ratio, OR odds ratio, SD senile dementia, VaD vascular dementia