| |
Clinical observation
|
In silico simulation
|
|---|
|
Before CRT
|
After CRT
|
Before CRT
|
After CRT
|
|---|
|
Age (years)
|
68
| | | |
|
Sex
|
Female
| | | |
|
Hypertension
|
No
| | | |
|
Diabetes
|
No
| | | |
|
Cause of HF
|
Nonischemic
| | | |
|
NYHA functional class
|
II
|
I
| | |
|
Blood pressure (mmHg)
|
120/68
|
118/55
|
120/68
|
124/69
|
|
ECG
|
|
PR interval (ms)
|
168
|
150
|
–
|
–
|
|
QRS duration (ms)
|
154
|
138
|
148
|
124
|
|
QRS complex
|
LBBB
|
pacing
| | |
|
Echocardiography
|
|
LVEDV (mL)
|
162
|
119
|
174
|
173
|
|
LVESV (mL)
|
114
|
69
|
116
|
104
|
|
LVEF (%)
|
29
|
42
|
33
|
40
|
|
Absolute ΔLVEF* (%)
| |
13
| |
7
|
|
Relative ΔLVEFa (%)
| |
31
| |
18
|
|
CRT response
| |
Responder
| |
Responder
|
- CRT cardiac resynchronization therapy, ECG electrocardiography, HF heart failure, IVCD intraventricular conduction delay, LBBB left bundle branch block, LVEDV left ventricular end-diastolic volume, LVEF left ventricular ejection fraction, LVESV left ventricular end-systolic volume, NYHA New York Heart Association,
- *absolute ΔLVEF = LVEFpost-CRT − LVEFpre-CRT
- arelative ΔLVEF = (LVEFpost-CRT − LVEFpre-CRT)/LVEFpre-CRT × 100
