Underutilization of anticoagulants in patients with nonvalvular atrial fibrillation in the era of non-vitamin K antagonist oral anticoagulants

Table 2 Adjusted odds ratios and 95% confidence intervals from the multiple logistic regression analysis of anticoagulant utilization

Explanatory variables		Anticoagulant utilization
Explanatory variables		Adj. OR	95% CI	p value
Age group	65–69 (R)
	70–74	1.167	1.023–1.332	0.022
	≥ 75	1.210	1.080–1.355	0.001
Sex	Male (R)
Sex	Female	1.061	0.971–1.160	0.192
CHF	No (R)
CHF	Yes	1.103	1.008–1.208	0.033
Hypertension	No (R)
Hypertension	Yes	1.644	1.445–1.869	< 0.001
Diabetes mellitus	No (R)
Diabetes mellitus	Yes	1.168	1.065–1.281	0.001
Prior stroke/TIA/TE	No (R)
Prior stroke/TIA/TE	Yes	1.444	1.289–1.619	< 0.001
Vascular disease	No(R)
Vascular disease	Yes	0.597	0.507–0.704	< 0.001
Anemia	No(R)
Anemia	Yes	0.648	0.560–0.751	< 0.001
Severe renal disease	No(R)
Severe renal disease	Yes	0.289	0.200–0.416	< 0.001
Prior hemorrhage diagnosis	No(R)
Prior hemorrhage diagnosis	Yes	0.610	0.502–0.741	< 0.001
Type of medical institution	Tertiary (R)
	General	0.624	0.563–0.691	< 0.001
	Primary & others	0.325	0.281–0.375	< 0.001
Region	Capital (R)
	Metropolitan	1.006	0.889–1.139	0.921
	Others	1.021	0.910–1.145	0.721
Aspirin use	No (R)
Aspirin use	Yes	0.097	0.085–0.110	< 0.001
AF type	Paroxysmal (R)
	Persistent	1.593	1.381–1.841	< 0.001
	Permanent	1.520	1.304–1.776	< 0.001
	Atrial flutter	0.530	0.283–1.004	0.048
	Others	1.183	1.067–1.313	0.001
c statistic	0.742
p value of Hosmer–Lemeshow test	0.384

Adj. OR adjusted odds ratio, AF atrial fibrillation, CHF congestive heart failure, CI confidence interval, R reference, TE thromboembolism, TIA transient ischemic attack

ISSN: 2466-1171