Table 1 Studies showing Insulin Resistance (IR) role in Atrial Fibrillation (AF)
Author | Place of study | Type of study | Year | Main findings | References |
|---|---|---|---|---|---|
Lee et al | Korea | A community-based, longitudinal study | 2020 | A significant association between atrial fibrillation and insulin resistance | [29] |
Polovina et al | Serbia | Editorial investigation | 2020 | Needs to promote further research | [83] |
Park et al | Korea | Prospective cohort study | 2019 | IR (HOMA-IR) was connected with AF independently of obesity in non-diabetics | [84] |
Chan et al | Taiwan | Experimental study on models | 2019 | Insulin resistance contributes to increased AF susceptibility | [32] |
Maria et al | United States | Experimental study on mice | 2018 | During diabetes, insulin deficiency could have resulted in alteration in energy production as well as glucose transport in the atria which can increase the susceptibility to AF | [37] |
Fontes et al | Boston | Community-based cohort | 2012 | They reported that there was no significant link between incident AF and insulin resistance | [3] |
Shigematsu Y | Japan | Cross-sectional study | 2011 | Insulin resistance may be a significant basic mechanism for the beginning of AF in hypertrophic cardiomyopathy (HCM) | [24] |
Östgren et al | Sweden | Community-based, cross-sectional observational study | 2004 | The combined occurrence of Hypertension and type 2 diabetes are linked to AF in which insulin resistance might be a common original mechanism | [31] |