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Table 2 Different features of commercially available automatic optimisation algorithms, according to manufacturers

From: ECG optimisation for CRT systems in the era of automatic algorithms: a comprehensive review

Features Medtronic AdaptiveCRT Boston SmartDelay Biotronik AutoAdapt Abbott Sync-AV Microport SonR
LV sensing capable  +   + 
Automatic run during follow-up  +   +   +   + 
LV preexcitation / LV pacing only  +   +   +   + fusion with RV always paced  + fusion with RV always paced
Intrinsic Conduction check  +   +   +   +   + weekly
Check LBBB pattern by EGM timing  + 
AV delay (A sense -RV sense) Range 80–140 ms  +  At 70% A sense-RV sense 50 ms shorter for each A sense-RV sense Range 30–250 ms
AV delay (A pace -RV sense) Range 100–18 ms  +  At 70% A pace-RV sense 50 ms shorter for each A pace-RV sense Range 30–250 ms + Extension 0–125 ms
VV offset 0–40 ms -Manually fixed Advance 40 ms for each A sense/pace-RV sense 10–80 ms (in step of 10 ms) Range 0–48 ms
Hemodynamic sensor  + 
Validated by available literature  +   +   +   + 
Available RV pacing minimisation  + MVP  + VIP  + AAI-SafeR
  1. LBBB left bundle branch block; LV left ventricle (pacing); RV right ventricle (pacing); VV offset VV delay programming with LV-RV which means LV pacing advances the RV pacing or the opposite; EGM electrogram; MVP Medtronic automatic algorithm to minimise RV pacing; VIP Abbott automatic algorithm minimise RV pacing; AAI-Safe R Microport automatic algorithm to minimise RV pacing