Table 2 IPTW-weighted event rate and hazard ratios for adverse cardiovascular outcomes according to resting heart rate
Event, n | Event rate (Crude/IPTW-weighted) | Unweighted HR (95% CI) | IPTW-weighted HR (95% CI) | p value | |
|---|---|---|---|---|---|
Composite outcome | |||||
≥ 100 bpm | 28 | 43.9/37.8 | Reference | Reference | |
80–99 bpm | 48 | 19.7/19.4 | 0.46 (0.29–0.74) | 0.52 (0.32–0.84) | 0.008 |
60–79 bpm | 63 | 21.6/21.5 | 0.51 (0.33–0.80) | 0.58 (0.37–0.92) | 0.021 |
≤ 59 bpm | 23 | 37.5/37.4 | 0.89 (0.51–1.54) | 1.01 (0.57–1.79) | 0.963 |
Myocardial infarction/CLI | |||||
≥ 100 bpm | 8 | 12.0/10.5 | Reference | Reference | |
80–99 bpm | 13 | 5.2/5.4 | 0.44 (0.18–1.07) | 0.52 (0.21–1.30) | 0.162 |
60–79 bpm | 17 | 5.7/5.5 | 0.49 (0.21–1.13) | 0.53 (0.23–1.25) | 0.151 |
≤ 59 bpm | 5 | 7.9/9.7 | 0.68 (0.22–2.09) | 0.96 (0.31–2.94) | 0.941 |
Heart failure hospitalization | |||||
≥ 100 bpm | 18 | 27.7/23.2 | Reference | Reference | |
80–99 bpm | 30 | 12.2/11.7 | 0.46 (0.25–0.82) | 0.51 (0.28–0.94) | 0.029 |
60–79 bpm | 42 | 14.3/14.3 | 0.54 (0.31–0.94) | 0.64 (0.36–1.12) | 0.119 |
≤ 59 bpm | 17 | 27.4/25.0 | 1.04 (0.53–2.01) | 1.11 (0.56–2.21) | 0.765 |
Cardiovascular death | |||||
≥ 100 bpm | 5 | 7.4/6.8 | Reference | Reference | |
80–99 bpm | 9 | 3.6/3.9 | 0.49 (0.16–1.47) | 0.56 (0.18–1.71) | 0.308 |
60–79 bpm | 6 | 2.0/2.1 | 0.27 (0.08–0.89) | 0.31 (0.09–1.04) | 0.057 |
≤ 59 bpm | 2 | 3.2/4.4 | 0.43 (0.08–2.23) | 0.63 (0.13–3.18) | 0.577 |